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How Did Hancock Become A Ghoul? [Solved]

Over time, he fell into a rut of depression and drug abuse, at some point taking an experimental, radioactive drug in an attempt to transform himself into a ghoul. The attempt was successful, and he today remarks that both the high and the subsequent transformation were “so worth it.”

(Hancock approval talk) Hancock’s brother and becoming a ghoul - Fallout 4

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Fallout 4: Ghouls Hate Hancock

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